Diode laser based light sources for biomedical applications

A. Müller1, S. Marschall1, O.B. Jensen1, J. Fricke2, H. Wenzel2, B. Sumpf2, and P.E. Andersen1

Published in:

Laser Photonics Rev., vol. 7, no. 5, pp. 605-627 (2013).

Copyright © 2013 by WILEY-VCH Verlag GmbH & Co. KGaA,Weinheim. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from WILEY-VCH Verlag GmbH & Co. KGaA,Weinheim.


Diode lasers are by far the most efficient lasers currently available. With the ever-continuing improvement in diode laser technology, this type of laser has become increasingly attractive for a wide range of biomedical applications. Compared to the characteristics of competing laser systems, diode lasers simultaneously offer tunability, high-power emission and compact size at fairly low cost. Therefore, diode lasers are increasingly preferred in important applications, such as photocoagulation, optical coherence tomography, diffuse optical imaging, fluorescence lifetime imaging, and terahertz imaging. This review provides an overview of the latest development of diode laser technology and systems and their use within selected biomedical applications.

1 DTU Fotonik, Department of Photonics Engineering, Technical University of Denmark, Frederiksborgvej 399, 4000 Roskilde, Denmark
2 Ferdinand-Braun-Institut, Leibniz-Institut für Höchstfrequenztechnik, Gustav-Kirchhoff-Straße 4, D-12489 Berlin, Germany


Diode lasers; Swept sources; Nonlinear frequency conversion; Gain switching; Diffuse imaging and spectroscopy; Photocoagulation; Optical coherence tomography; Fluorescence diagnostics.